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BioNTech SE (short for Biopharmaceutical New Technologies) is a German biotechnology company based in Mainz that develops and manufactures active immunotherapies for patient-specific approaches to the treatment of diseases. It develops pharmaceutical candidates based on messenger RNA (mRNA) for use as individualized cancer immunotherapies, as vaccines against infectious diseases and as protein replacement therapies for rare diseases, and also engineered cell therapy, novel antibodies, and small molecule immunomodulators as treatment options for cancer.

The company has developed an mRNA-based human therapeutic for intravenous administration to bring individualized mRNA-based cancer immunotherapy to clinical trials and to establish its own manufacturing process. In 2020, BioNTech’s RNA vaccine candidate for preventing COVID-19 infections, BNT162b2, was in Phase III clinical trials in the United States. On 2 December 2020, temporary Human Medicines Regulations (HMR) authorization was granted by the United Kingdom government for BNT162b2 vaccinations within the UK.

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